merlin-expo:models:man
Table of Contents
Resources
Description
The term pharmaco/toxicokinetic refers to the prediction of the time-dependent concentrations of a compound in a living organism. Physiologically based pharmacokinetic (PBPK) modelling consists in describing the relationship between the external dose and the internal dosimetry using parameters related to the anatomy and the physiology of the individual and using physico-chemical properties of the contaminants. The goal of the PBPK model is to simulate the toxicokinetics of contaminants in humans, i.e. the amounts or concentrations in different organs/tissues, under various exposure conditions.
Interface
Inputs
| Name | Provided by | Comment |
|---|---|---|
| Age at the beginning of the simulation | Human intake,Population intake | |
| Concentration of contaminant inhaled | Human intake,Population intake | |
| rate of the amount of contaminant ingested | Human intake,Population intake |
Working with the man model
See also
merlin-expo/models/man.txt · Last modified: 2015/08/13 14:25 (external edit)
Except where otherwise noted, content on this wiki is licensed under the following license: CC Attribution-Share Alike 4.0 International
